Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 9/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 2/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22995062 | 0.83 | LTA4H (0.41) | L3MBTL1LTA4HFFAR1KDM4EMEN1 | |
| SCHEMBL20803021 | 0.82 | LTA4H (0.42) | OPRL1LTA4HFFAR1KDM4EMEN1 | |
| SCHEMBL19034507 | 0.70 | SLC5A1 (0.43) | L3MBTL1LTA4HMEN1KMT2A | |
| SCHEMBL22995059 | 0.70 | SLC5A1 (0.59) | L3MBTL1LTA4HKDM4EMEN1ALDH1A1 | |
| SCHEMBL21029204 | 0.68 | LTA4H (0.46) | LTA4HKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL9234531 | 0.68 | LTA4H (0.49) | LTA4H | |
| SCHEMBL21218509 | 0.68 | LMNA (0.55) | L3MBTL1LTA4H | |
| SCHEMBL8095627 | 0.67 | LTA4H (0.53) | LTA4HFFAR1 | |
| SCHEMBL20803510 | 0.67 | SLC5A1 (0.60) | L3MBTL1LTA4HDRD2DRD4DRD3 | |
| SCHEMBL28131751 | 0.66 | LTA4H (0.64) | L3MBTL1LTA4HMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489226-A1 | INHIBITORS OF SODIUM GLUCOSE COTRANSPORTER 1 | Lexicon Pharmaceuticals, Inc. (US) | 2019-05-29 | — | — | EP | disclosed |