Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21029611 | 0.89 | SLC7A5 (0.45) | SLC7A5HDAC1LTA4HAPPALDH1A1 | |
| SCHEMBL21029376 | 0.87 | SLC7A5 (0.48) | SLC7A5LTA4HALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL3745863 | 0.85 | SLC7A5 (0.44) | SLC7A5LTA4HAPPALDH1A1CYP3A4 | |
| SCHEMBL3745868 | 0.85 | SLC7A5 (0.44) | SLC7A5LTA4HAPPALDH1A1CYP3A4 | |
| SCHEMBL24899365 | 0.85 | APP (0.41) | HDAC3HDAC1HDAC2HDAC8MMP13 | |
| SCHEMBL5367312 | 0.85 | ALDH1A1 (0.51) | SLC7A5HDAC3HDAC1HDAC2HDAC8 | |
| Hydrochloric Acid SCHEMBL27548705 | 0.83 | ALDH1A1 (0.53) | SLC7A5HDAC3HDAC1HDAC2HDAC8 | |
| Hydrochloric Acid SCHEMBL5367308 | 0.83 | ALDH1A1 (0.53) | SLC7A5HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL19088473 | 0.83 | SLC7A5 (0.44) | SLC7A5LTA4HAPPALDH1A1CYP3A4 | |
| SCHEMBL29551946 | 0.83 | SLC7A5 (0.44) | SLC7A5LTA4HAPPALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10301286-B2 | Piperazine derivative | ASTELLAS PHARMA INC. (JP) | 2019-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10301286-B2 | Piperazine derivative | GPR4, MC4R, TRPC4 | SLC7A5 2250/4885HDAC3 867/4885HDAC1 1646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.