Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21029427 | 0.89 | SLC7A5 (0.45) | SLC7A5ALDH1A1KDM4EUSP2EGFR | |
| SCHEMBL21029376 | 0.87 | SLC7A5 (0.48) | SLC7A5ALDH1A1KDM4EUSP2EGFR | |
| SCHEMBL30191722 | 0.85 | SLC7A5 (0.44) | SLC7A5ALDH1A1KDM4EUSP2EGFR | |
| SCHEMBL19088473 | 0.85 | SLC7A5 (0.44) | SLC7A5ALDH1A1KDM4EUSP2EGFR | |
| SCHEMBL18256468 | 0.85 | SLC7A5 (0.44) | SLC7A5ALDH1A1KDM4EUSP2EGFR | |
| SCHEMBL29551946 | 0.85 | SLC7A5 (0.44) | SLC7A5ALDH1A1KDM4EUSP2EGFR | |
| SCHEMBL18481064 | 0.85 | APP (0.38) | SLC7A5ALOX15PTPN1APPHDAC1 | |
| SCHEMBL5363551 | 0.85 | ALDH1A1 (0.51) | SLC7A5ALDH1A1KDM4EUSP2EGFR | |
| Hydrochloric Acid SCHEMBL5363548 | 0.83 | ALDH1A1 (0.53) | SLC7A5ALDH1A1KDM4EUSP2EGFR | |
| Hydrochloric Acid SCHEMBL27466206 | 0.83 | ALDH1A1 (0.53) | SLC7A5ALDH1A1KDM4EUSP2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10301286-B2 | Piperazine derivative | ASTELLAS PHARMA INC. (JP) | 2019-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10301286-B2 | Piperazine derivative | GPR4, MC4R, TRPC4 | SLC7A5 2250/4885ALDH1A1 2695/4885KDM4E 1279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.