SCHEMBL21029949

SCHEMBL21029949

Cc1ccc(C(=Cc2ccc(N(c3ccc(C=C(c4ccc(C)cc4)c4ccc(C)cc4)cc3)c3ccc(C)cc3C)cc2)c2ccc(C)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 7/20 0.47
ESR1 P03372 2/20 0.40
ESR2 Q92731 1/20 0.40
MAPT P10636 4/20 0.39
ALDH1A1 P00352 3/20 0.39
KDM4E B2RXH2 3/20 0.39
HPGD P15428 1/20 0.39
NPSR1 Q6W5P4 2/20 0.36
JAK2 O60674 1/20 0.36
HTT P42858 1/20 0.36
RAB9A P51151 1/20 0.36
ATM Q13315 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12576286 1.00 PTGS2 (0.47) PTGS2ESR1ESR2MAPTALDH1A1
SCHEMBL25053719 0.96 PTGS2 (0.43) PTGS2ESR1ESR2MAPTALDH1A1
SCHEMBL13050002 0.95 PTGS2 (0.51) PTGS2ESR1ESR2MAPTNPSR1
SCHEMBL14769858 0.95 PTGS2 (0.51) PTGS2ESR1ESR2MAPTNPSR1
SCHEMBL12576285 0.95 PTGS2 (0.51) PTGS2ESR1ESR2MAPTNPSR1
SCHEMBL12576284 0.93 PTGS2 (0.42) PTGS2ESR1ESR2MAPTALDH1A1
SCHEMBL19795461 0.93 PTGS2 (0.49) PTGS2ESR1MAPTALDH1A1HPGD
SCHEMBL10057475 0.92 PTGS2 (0.47) PTGS2ESR1MAPTALDH1A1NPSR1
SCHEMBL17321091 0.88 TRPM8 (0.42) PTGS2ESR1ESR2MAPTALDH1A1
SCHEMBL13679109 0.88 PTGS2 (0.44) PTGS2ESR1MAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11703773-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2023-07-18 US disclosed
US-11703773-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2023-07-18 US disclosed
EP-3575879-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC IMAGE-FORMING APPARATUS CANON KK (JP) 2022-05-25 EP disclosed
EP-3575878-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KK (JP) 2022-05-11 EP disclosed
US-11150566-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2021-10-19 US disclosed
US-20210240094-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 2021-08-05 US disclosed
US-20200393771-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2020-12-17 US disclosed
US-10831118-B2 Electrophotographic photosensitive member and method for producing electrophotographic photosensitive member CANON KABUSHIKI KAISHA (JP) 2020-11-10 US disclosed
US-10663913-B2 Process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2020-05-26 US disclosed
US-10558133-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2020-02-11 US disclosed
US-10545453-B2 Process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-28 US disclosed
US-20190163119-A1 PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2019-05-30 US disclosed
US-20190163118-A1 PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2019-05-30 US disclosed