Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL909718 | 0.85 | USP2 (0.56) | MAPTL3MBTL1PIK3CAHTTSMN1; SMN2 | |
| SCHEMBL24851270 | 0.83 | KMT2A (0.46) | MAPTL3MBTL1PIK3CASMN1; SMN2MEN1 | |
| SCHEMBL14387482 | 0.75 | MEN1 (0.50) | MAPTPIK3CAHTTSMN1; SMN2MEN1 | |
| SCHEMBL28604242 | 0.75 | L3MBTL1 (0.53) | MAPTL3MBTL1PIK3CAHTTSMN1; SMN2 | |
| SCHEMBL15879042 | 0.75 | MEN1 (0.50) | MAPTPIK3CAHTTSMN1; SMN2MEN1 | |
| SCHEMBL1308905 | 0.75 | MAPT (0.61) | MAPTL3MBTL1PIK3CAHTTSMN1; SMN2 | |
| SCHEMBL15557358 | 0.74 | HTT (0.51) | MAPTL3MBTL1PIK3CAHTTSMN1; SMN2 | |
| SCHEMBL23505759 | 0.74 | SORD (0.37) | MAPTL3MBTL1PIK3CAMAPK1MEN1 | |
| SCHEMBL1310780 | 0.73 | MAPT (0.60) | MAPTL3MBTL1PIK3CAHTTSMN1; SMN2 | |
| SCHEMBL1409174 | 0.72 | GPR119 (0.49) | MAPTPIK3CASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019101853-A1 | TREATMENT OF SKIN DISORDERS | PIQUR THERAPEUTICS AG (CH) | 2019-05-31 | — | — | WO | disclosed |