Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | APAF1 | O14727 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | NSD2 | O96028 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.50 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | GALK1 | P51570 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15686104 | 0.73 | MAPT (0.56) | TDP2MAPTAPAF1KDM4ENSD2 | |
| SCHEMBL15686155 | 0.70 | ALDH1A1 (0.56) | TDP2MAPTAPAF1KDM4ENSD2 | |
| SCHEMBL15642099 | 0.69 | ALDH1A1 (0.52) | TDP2MAPTAPAF1KDM4ENSD2 | |
| SCHEMBL28600721 | 0.69 | SIGMAR1 (0.40) | AVPR1A | |
| SCHEMBL15642398 | 0.68 | TDP2 (0.53) | TDP2MAPTAPAF1KDM4ENSD2 | |
| SCHEMBL29368014 | 0.68 | MAPT (0.50) | TDP2MAPTAPAF1KDM4ENSD2 | |
| SCHEMBL15642248 | 0.68 | MAPT (0.50) | TDP2MAPTAPAF1KDM4ENSD2 | |
| SCHEMBL15642056 | 0.67 | MAPT (0.56) | TDP2MAPTAPAF1KDM4ENSD2 | |
| SCHEMBL28598588 | 0.66 | MAPK1 (0.39) | SMN1; SMN2MAPK1AVPR1A | |
| SCHEMBL28335423 | 0.66 | SIGMAR1 (0.38) | AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2722042-B1 | INDANONE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALTS OR OPTICAL ISOMERS THEREOF, PREPARATION METHOD FOR SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING VIRAL DISEASES | KOREA RES INST CHEMICAL TECH (KR) | 2019-05-29 | — | — | EP | disclosed |