Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | VHL | P40337 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5315064 | 0.76 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2HCAR2VHL | |
| SCHEMBL21030775 | 0.74 | TRPM8 (0.34) | — | |
| SCHEMBL17809498 | 0.72 | — | — | |
| SCHEMBL21030776 | 0.70 | — | — | |
| SCHEMBL24710858 | 0.70 | — | — | |
| SCHEMBL10158198 | 0.68 | HCAR2 (0.38) | ALDH1A1SMN1; SMN2HCAR2VHLKMT2A | |
| SCHEMBL10158190 | 0.66 | HCAR2 (0.32) | ALDH1A1SMN1; SMN2HCAR2 | |
| SCHEMBL468941 | 0.65 | — | — | |
| SCHEMBL18881405 | 0.65 | POLB (0.38) | ALDH1A1SMN1; SMN2HCAR2VHLMEN1 | |
| SCHEMBL28222965 | 0.64 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2HCAR2VHLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019101906-A1 | NOVEL BRADYKININ B2 RECEPTOR ANTAGONISTS | PHARVARIS B.V. (NL) | 2019-05-31 | — | — | WO | disclosed |