Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21030772 | 0.74 | ALDH1A1 (0.33) | — | |
| SCHEMBL22334179 | 0.73 | — | — | |
| SCHEMBL24427012 | 0.71 | — | — | |
| SCHEMBL26524048 | 0.70 | — | — | |
| SCHEMBL23966742 | 0.66 | TRPM8 (0.41) | TRPM8 | |
| SCHEMBL24960540 | 0.64 | TRPM8 (0.36) | TRPM8 | |
| SCHEMBL12425237 | 0.63 | TRPM8 (0.47) | TRPM8 | |
| SCHEMBL27695174 | 0.63 | — | — | |
| SCHEMBL13887438 | 0.63 | — | — | |
| SCHEMBL18119644 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3998259-A1 | NOVEL BRADYKININ B2 RECEPTOR ANTAGONISTS | Pharvaris Netherlands B.V. (NL) | 2022-05-18 | — | — | EP | disclosed |
| WO-2019101906-A1 | NOVEL BRADYKININ B2 RECEPTOR ANTAGONISTS | PHARVARIS B.V. (NL) | 2019-05-31 | — | — | WO | disclosed |