SCHEMBL21031225

SCHEMBL21031225

Cn1c2ccccc2c2cc(-c3ccc4c(c3)c3ccccc3n4-c3ccc4ccccc4c3)ccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.48
MAPT P10636 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
KMT2A Q03164 2/20 0.48
HPGD P15428 2/20 0.48
ALDH1A1 P00352 2/20 0.48
MEN1 O00255 1/20 0.48
HTT P42858 1/20 0.48
HSD17B10 Q99714 1/20 0.48
GPR3 P46089 1/20 0.46
ATM Q13315 1/20 0.40
RXRA P19793 1/20 0.39
RXRB P28702 1/20 0.39
HTR3A P46098 1/20 0.39
TUBB4A P04350 1/20 0.38
TUBB P07437 1/20 0.38
TUBA3C P0DPH7 1/20 0.38
TUBA1B P68363 1/20 0.38
TUBA4A P68366 1/20 0.38
TUBB4B P68371 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21032329 0.96 L3MBTL1 (0.44) KDM4EMAPTL3MBTL1KMT2AHPGD
SCHEMBL21030899 0.96 RXRA (0.45) KDM4EMAPTL3MBTL1KMT2AHPGD
SCHEMBL15480403 0.93 KDM4E (0.46) KDM4EL3MBTL1HPGDALDH1A1ATM
SCHEMBL11981041 0.93 KDM4E (0.46) KDM4EL3MBTL1HPGDALDH1A1ATM
SCHEMBL30475208 0.93 KDM4E (0.46) KDM4EL3MBTL1HPGDALDH1A1ATM
SCHEMBL21030550 0.92 KDM4E (0.42) KDM4EMAPTL3MBTL1KMT2AHPGD
SCHEMBL21032320 0.92 KDM4E (0.42) KDM4EMAPTL3MBTL1KMT2AHPGD
SCHEMBL25847208 0.92 KDM4E (0.46) KDM4EMAPTL3MBTL1KMT2AHPGD
SCHEMBL21031227 0.92 GPR3 (0.43) KDM4EMAPTL3MBTL1KMT2AHPGD
SCHEMBL23264317 0.91 KDM4E (0.44) KDM4EL3MBTL1HPGDALDH1A1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230276690-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-08-31 US disclosed
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes IDEMITSU KOSAN CO., LTD. (JP) 2023-07-04 US disclosed
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes IDEMITSU KOSAN CO., LTD. (JP) 2023-07-04 US disclosed
US-20190161497-A1 SPECIFICALLY SUBSTITUTED BENZOFURO- AND BENZOTHIENOQUINOLINES FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO., LTD. (JP) 2019-05-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230276690-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME L1CAM, TELO2, LIMS1 KDM4E 1506/4885MAPT 2197/4885L3MBTL1 77/4885
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes KCNQ2, KCNQ1, KCNQ4 KDM4E 962/4885MAPT 611/4885L3MBTL1 1618/4885
US-20190161497-A1 SPECIFICALLY SUBSTITUTED BENZOFURO- AND BENZOTHIENOQUINOLINES FOR ORGANIC LIGHT EMITTING DIODES KCNQ2, KCNQ1, KCNQ4 KDM4E 962/4885MAPT 611/4885L3MBTL1 1618/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.