SCHEMBL21031282

SCHEMBL21031282

c1ccc(-c2ccc(-c3cc(-c4c5ccccc5nc5c4sc4ccccc45)nc(-c4ccccc4)n3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.42
KMT2A Q03164 6/20 0.42
HPGD P15428 5/20 0.42
ALDH1A1 P00352 4/20 0.42
MAPT P10636 4/20 0.42
NTSR1 P30989 1/20 0.42
DHODH Q02127 1/20 0.40
ACHE P22303 1/20 0.38
LMNA P02545 3/20 0.38
KDM4E B2RXH2 3/20 0.38
GLA P06280 1/20 0.38
ADORA2A P29274 1/20 0.37
ADORA1 P30542 1/20 0.37
TNKS O95271 1/20 0.37
TNKS2 Q9H2K2 1/20 0.37
LIMK1 P53667 2/20 0.36
SCD O00767 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
PDE10A Q9Y233 1/20 0.36
ACACA Q13085 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21030944 0.97 MEN1 (0.41) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL22763764 0.95 MEN1 (0.42) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL22763760 0.95 MEN1 (0.42) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL21031032 0.95 MEN1 (0.42) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL21031274 0.95 MEN1 (0.42) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL21032090 0.94 MEN1 (0.43) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL21031192 0.94 MEN1 (0.43) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL21031280 0.93 MEN1 (0.36) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL21031281 0.92 DHODH (0.42) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL21031390 0.92 MEN1 (0.41) MEN1KMT2AHPGDALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes IDEMITSU KOSAN CO., LTD. (JP) 2023-07-04 US disclosed
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes IDEMITSU KOSAN CO., LTD. (JP) 2023-07-04 US disclosed
US-20230009458-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-01-12 US disclosed
US-20220173334-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS EQUIPPED WITH THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2022-06-02 US disclosed
US-20220165964-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS PROVIDED WITH THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2022-05-26 US disclosed
US-20220059775-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS USING THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2022-02-24 US disclosed
US-20210296591-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPLIANCE USING THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2021-09-23 US disclosed
US-20190161497-A1 SPECIFICALLY SUBSTITUTED BENZOFURO- AND BENZOTHIENOQUINOLINES FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO., LTD. (JP) 2019-05-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes KCNQ2, KCNQ1, KCNQ4 MEN1 3802/4885KMT2A 1221/4885HPGD 2093/4885
US-20220165964-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS PROVIDED WITH THE SAME LEF1, OR10J3, RER1 MEN1 1172/4885KMT2A 3238/4885HPGD 3898/4885
US-20190161497-A1 SPECIFICALLY SUBSTITUTED BENZOFURO- AND BENZOTHIENOQUINOLINES FOR ORGANIC LIGHT EMITTING DIODES KCNQ2, KCNQ1, KCNQ4 MEN1 3802/4885KMT2A 1221/4885HPGD 2093/4885
US-20210296591-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPLIANCE USING THE SAME OLA1, AOC1, ODC1 MEN1 936/4885KMT2A 1063/4885HPGD 3844/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.