Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19594830 | 0.78 | TSHR (0.43) | TSHRALDH1A1TDP1L3MBTL1PPARG | |
| SCHEMBL26778457 | 0.77 | TSHR (0.42) | TSHRALDH1A1TDP1L3MBTL1PPARG | |
| SCHEMBL16782927 | 0.77 | TSHR (0.42) | TSHRALDH1A1TDP1L3MBTL1PPARG | |
| SCHEMBL23065597 | 0.75 | TSHR (0.41) | TSHRALDH1A1TDP1L3MBTL1PPARG | |
| SCHEMBL28225850 | 0.75 | TSHR (0.41) | TSHRALDH1A1TDP1L3MBTL1PPARG | |
| SCHEMBL19257403 | 0.73 | TSHR (0.39) | TSHRALDH1A1TDP1L3MBTL1PPARG | |
| SCHEMBL16782926 | 0.73 | CA1 (0.40) | TSHRALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL243431 | 0.72 | TSHR (0.56) | TSHRALDH1A1TDP1L3MBTL1PPARG | |
| SCHEMBL334176 | 0.72 | TSHR (0.50) | TSHRALDH1A1TDP1L3MBTL1POLB | |
| SCHEMBL29587773 | 0.72 | TSHR (0.38) | TSHRALDH1A1TDP1L3MBTL1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10617662-B2 | Autophagy activation-induced compound for improving skin inflammation for aging | INCOSPHARM CORPORATION (KR) | 2020-04-14 | — | — | US | disclosed |
| US-20190160033-A1 | NOVEL AUTOPHAGY ACTIVATION-INDUCED COMPOUND FOR IMPROVING SKIN INFLAMMATION FOR AGING | INCOSPHARM CORPORATION (KR) | 2019-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10617662-B2 | Autophagy activation-induced compound for improving skin inflammation for aging | TFEB, ATG7, BECN1 | TSHR 4768/4885ALDH1A1 4347/4885TDP1 2258/4885 |
| US-20190160033-A1 | NOVEL AUTOPHAGY ACTIVATION-INDUCED COMPOUND FOR IMPROVING SKIN INFLAMMATION FOR AGING | TFEB, ATG7, BECN1 | TSHR 4826/4885ALDH1A1 4369/4885TDP1 2196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.