Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RHOA | P61586 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31009842 | 0.73 | CA2 (0.50) | GPR3MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL8178818 | 0.73 | GPR3 (0.46) | GPR3MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL8024080 | 0.73 | GPR3 (0.46) | GPR3MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL10242855 | 0.73 | CA2 (0.50) | GPR3MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL10860632 | 0.73 | GPR3 (0.46) | GPR3MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL6337534 | 0.73 | GPR3 (0.46) | GPR3MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL17121934 | 0.73 | GPR3 (0.46) | GPR3MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL21032222 | 0.71 | PTGDR2 (0.34) | EP300IMPDH2IMPDH1MAOB | |
| SCHEMBL9565755 | 0.70 | MAOB (0.50) | GPR3MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL8795307 | 0.68 | MAPT (0.56) | GPR3MAPTALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489233-B1 | INDOLE DERIVATIVE USED AS CRTH2 INHIBITOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2022-01-12 | — | — | EP | disclosed |
| EP-3489233-A1 | INDOLE DERIVATIVE USED AS CRTH2 INHIBITOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2019-05-29 | — | — | EP | disclosed |