Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.32 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21266565 | 0.77 | CA1 (0.41) | PTGDR2MAOAMAOBCDC25BIMPDH2 | |
| SCHEMBL21032218 | 0.71 | GPR3 (0.46) | MAOBIMPDH2IMPDH1EP300 | |
| SCHEMBL21157146 | 0.70 | GPR3 (0.44) | MAOAMAOBCDC25B | |
| SCHEMBL21917575 | 0.67 | EGFR (0.38) | MAOAMAOBCDC25BIMPDH2IMPDH1 | |
| SCHEMBL8229992 | 0.66 | PTGDR2 (0.33) | PTGDR2 | |
| SCHEMBL18818680 | 0.65 | CDC25B (0.32) | CDC25B | |
| SCHEMBL8285749 | 0.61 | LMNA (0.39) | MAOAMAOBCDC25B | |
| SCHEMBL21032156 | 0.61 | VEGFA (0.40) | MAOAMAOBCDC25B | |
| SCHEMBL21157145 | 0.61 | GPR3 (0.44) | MAOAMAOBCDC25B | |
| SCHEMBL22827924 | 0.60 | MAOA (0.37) | MAOAMAOBCDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489233-A1 | INDOLE DERIVATIVE USED AS CRTH2 INHIBITOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2019-05-29 | — | — | EP | disclosed |