SCHEMBL2103257

SCHEMBL2103257

CCN[Si](Cl)(c1ccccc1)N(C)C

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.32
LMNA P02545 1/20 0.32
ALDH1A1 P00352 2/20 0.31
TSHR P16473 1/20 0.31
TP53 P04637 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2103007 0.82 KCNN4 (0.31) KCNN4
SCHEMBL2102482 0.79 TSHR (0.32) LMNATSHR
SCHEMBL2101654 0.75 KCNN4 (0.34) KCNN4ALDH1A1TSHRTP53HTT
SCHEMBL2101901 0.75 KCNN4 (0.34) KCNN4ALDH1A1TSHRTP53HTT
SCHEMBL2103088 0.75 KCNN4 (0.34) KCNN4ALDH1A1TSHRTP53HTT
SCHEMBL2099500 0.74 KCNN4 (0.37) KCNN4LMNAALDH1A1TP53HTT
SCHEMBL2100205 0.74 KCNN4 (0.37) KCNN4LMNAALDH1A1TP53HTT
SCHEMBL2103096 0.74 KCNN4 (0.41) KCNN4LMNAALDH1A1TP53HTT
SCHEMBL2270811 0.73 KCNN4 (0.38) KCNN4ALDH1A1TSHRTP53
SCHEMBL2100216 0.72 ESR1 (0.40) KCNN4LMNAALDH1A1TP53HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-8164166-B2 Interfacial roughness reducing film, wiring layer, semiconductor device, and method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2012-04-24 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed
US-20090085170-A1 INTERFACIAL ROUGHNESS REDUCING FILM, WIRING LAYER, SEMICONDUCTOR DEVICE, AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2009-04-02 US disclosed