Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 5/20 | 0.48 |
| ▸ | ADH1A | P07327 | 5/20 | 0.48 |
| ▸ | ADH1C | P00326 | 4/20 | 0.48 |
| ▸ | ADH7 | P40394 | 3/20 | 0.48 |
| ▸ | ADH4 | P08319 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL798497 | 0.87 | ADH1A (0.60) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL15314039 | 0.82 | ADH1A (0.60) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL798471 | 0.82 | ADH1A (0.60) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL19086672 | 0.79 | — | — | |
| SCHEMBL19086673 | 0.79 | — | — | |
| SCHEMBL13866435 | 0.79 | — | — | |
| SCHEMBL1767331 | 0.76 | — | — | |
| SCHEMBL12108510 | 0.76 | ADH1B (0.43) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL5637702 | 0.73 | ADH1B (0.44) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL2745491 | 0.73 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489236-A1 | PROCESS FOR THE PREPARATION OF FUSED HETEROAROMATIC PYRROLIDINONES | Takeda Pharmaceutical Company Limited (JP) | 2019-05-29 | — | — | EP | disclosed |