Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21033204 | 0.82 | ROCK2 (0.52) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL21033191 | 0.79 | NPC1 (0.56) | RAB9ANPC1POLBKMT2AMEN1 | |
| SCHEMBL21033199 | 0.79 | ROCK2 (0.50) | MAPTRAB9ANPC1POLBKMT2A | |
| SCHEMBL21033678 | 0.78 | RAB9A (0.53) | RAB9ANPC1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL26633385 | 0.77 | ADRA2A (0.44) | MAPTRAB9ANPC1POLBKMT2A | |
| SCHEMBL21033196 | 0.77 | NPC1 (0.62) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL5060694 | 0.76 | ADRA2A (0.47) | MAPTRAB9ANPC1SMN1; SMN2ADRA2A | |
| SCHEMBL21032816 | 0.75 | RAB9A (0.49) | RAB9ANPC1POLBKMT2AMEN1 | |
| SCHEMBL21033679 | 0.74 | NPC1 (0.68) | MAPTRAB9ANPC1CASP3SENP7 | |
| SCHEMBL21032814 | 0.74 | NPC1 (0.68) | RAB9ANPC1CASP3SENP7POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104199-A1 | SMALL MOLECULE AGONISTS AND ANTAGONISTS OF NR2F6 ACTIVITY | REGEN BIOPHARMA INC. (US) | 2019-05-31 | — | — | WO | disclosed |
| WO-2019104201-A1 | SMALL MOLECULE AGONISTS AND ANTAGONISTS OF NR2F6 ACTIVITY IN NON-HUMANS | Zander Therapeutics, Inc. (US) | 2019-05-31 | — | — | WO | disclosed |