SCHEMBL21032830

SCHEMBL21032830

Cc1cc(-c2ccccc2-n2c3ccccc3c3ccccc32)ccc1-n1c2ccc(-c3ccccc3)cc2c2cc(-c3ccccc3)ccc21

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSPO P30536 4/20 0.40
KDM4E B2RXH2 1/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
HTR7 P34969 1/20 0.36
ALDH1A1 P00352 2/20 0.36
NPY5R Q15761 2/20 0.36
TYMS P04818 1/20 0.35
DNM1 Q05193 1/20 0.33
NR4A2 P43354 2/20 0.32
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21031696 1.00 TSPO (0.40) TSPOKDM4EATML3MBTL1HTR7
SCHEMBL21032828 0.90 HTR7 (0.42) KDM4EATML3MBTL1HTR7ALDH1A1
SCHEMBL25672030 0.89 L3MBTL1 (0.50) TSPOKDM4EATML3MBTL1ALDH1A1
SCHEMBL22876426 0.87 ATM (0.44) TSPOKDM4EATML3MBTL1HTR7
SCHEMBL25671847 0.87 ATM (0.44) TSPOKDM4EATML3MBTL1HTR7
SCHEMBL22876298 0.87 ATM (0.44) TSPOKDM4EATML3MBTL1HTR7
SCHEMBL21032832 0.87 ATM (0.44) TSPOKDM4EATML3MBTL1HTR7
SCHEMBL25936862 0.86 TSPO (0.41) TSPOKDM4EATML3MBTL1HTR7
SCHEMBL24923755 0.86 ATM (0.41) TSPOKDM4EATML3MBTL1HTR7
SCHEMBL22172808 0.86 KDM4E (0.41) TSPOKDM4EATML3MBTL1HTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019101594-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2019-05-31 WO disclosed