Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20435665 | 0.88 | THRB (0.58) | TP53KMT2AHPGDTHRBPOLB | |
| SCHEMBL20435658 | 0.83 | CA12 (0.58) | TP53KMT2AMEN1NPSR1HPGD | |
| SCHEMBL20435653 | 0.82 | CA12 (0.56) | KMT2AMEN1HPGDALDH1A1LMNA | |
| SCHEMBL20435657 | 0.82 | TSHR (0.58) | KMT2AMEN1NPSR1HPGDALDH1A1 | |
| SCHEMBL20435668 | 0.82 | CA12 (0.56) | KMT2AMEN1NPSR1HPGDPOLB | |
| SCHEMBL20435663 | 0.81 | LMNA (0.54) | KMT2AMEN1NPSR1HPGDALDH1A1 | |
| SCHEMBL20435655 | 0.81 | CA2 (0.60) | KMT2AMEN1HPGDALDH1A1TSHR | |
| SCHEMBL20435710 | 0.76 | POLB (0.54) | TP53KMT2AMEN1NPSR1THRB | |
| SCHEMBL20435713 | 0.75 | TP53 (0.64) | TP53KMT2ATHRBPOLBALDH1A1 | |
| SCHEMBL20435715 | 0.74 | TP53 (0.60) | TP53THRBPOLBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104201-A1 | SMALL MOLECULE AGONISTS AND ANTAGONISTS OF NR2F6 ACTIVITY IN NON-HUMANS | Zander Therapeutics, Inc. (US) | 2019-05-31 | — | — | WO | disclosed |
| WO-2019104199-A1 | SMALL MOLECULE AGONISTS AND ANTAGONISTS OF NR2F6 ACTIVITY | REGEN BIOPHARMA INC. (US) | 2019-05-31 | — | — | WO | disclosed |