Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.31 |
| ▸ | RAB9A | P51151 | 4/20 | 0.31 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21033570 | 0.65 | FYN (0.42) | KDM4ERAB9ANPC1RXFP1KMT2A | |
| SCHEMBL21033137 | 0.60 | EGLN1 (0.34) | KDM4ERAB9ANPC1 | |
| SCHEMBL20402695 | 0.59 | RAB9A (0.34) | KDM4ERAB9ANPC1RXFP1KMT2A | |
| SCHEMBL18929122 | 0.57 | — | — | |
| SCHEMBL31035823 | 0.56 | KDM4E (0.60) | KDM4ERAB9ANPC1RXFP1KMT2A | |
| SCHEMBL21033571 | 0.55 | METTL3 (0.37) | KDM4ERAB9AKMT2AL3MBTL1 | |
| SCHEMBL20402697 | 0.55 | AHR (0.31) | — | |
| SCHEMBL23529941 | 0.53 | KDM4E (0.46) | KDM4ERAB9ANPC1RXFP1KMT2A | |
| SCHEMBL21033473 | 0.53 | KDM4E (0.67) | KDM4ERAB9ANPC1RXFP1KMT2A | |
| SCHEMBL22296023 | 0.52 | HTT (0.37) | KDM4ERAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019102494-A1 | HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS | JUBILANT BIOSYS LIMITED (IN) | 2019-05-31 | — | — | WO | disclosed |