SCHEMBL21034010

SCHEMBL21034010

Cc1cncnc1-c1cccc2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.44
CYP3A4 P08684 2/20 0.44
CYP2D6 P10635 2/20 0.44
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
ALDH1A1 P00352 2/20 0.42
CYP2A6 P11509 2/20 0.42
CYP17A1 P05093 1/20 0.41
KDR P35968 1/20 0.40
BCHE P06276 1/20 0.40
DHFR P00374 1/20 0.40
RIPK2 O43353 1/20 0.39
PRKD3 O94806 1/20 0.39
ABL1 P00519 1/20 0.39
FYN P06241 1/20 0.39
SRC P12931 1/20 0.39
CDK2 P24941 1/20 0.39
CSK P41240 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16805023 0.78 CYP17A1 (0.55) CYP1A2CYP3A4CYP2D6ALDH1A1CYP2A6
SCHEMBL21128378 0.77 CYP1A2 (0.51) CYP1A2CYP3A4CYP2D6ALDH1A1MAPK11
SCHEMBL21033797 0.76 ALDH1A1 (0.50) CYP3A4CA12CA1CA2CA9
SCHEMBL19594886 0.72 SIGMAR1 (0.40) CYP1A2CYP3A4CYP2D6ALDH1A1CYP2A6
SCHEMBL21034043 0.72 TNF (0.50) CYP1A2CA12CA1CA2CA9
SCHEMBL28102668 0.72 DPP4 (0.42) CYP1A2CYP3A4CYP2D6ALDH1A1KDM4E
SCHEMBL1603653 0.71 DHFR (0.44) CA12CA1CA2CA9ALDH1A1
SCHEMBL9028766 0.71 ATM (0.46) CYP1A2CYP3A4CYP2D6ALDH1A1CYP2A6
SCHEMBL2951873 0.71 ALDH1A1 (0.44) ALDH1A1CYP2A6BCHEDHFRCYP11B2
SCHEMBL30125497 0.71 ALDH1A1 (0.44) ALDH1A1CYP2A6BCHEDHFRCYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10305041-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2019-05-28 US disclosed