Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8148844 | 0.82 | RECQL (0.46) | POLBRECQLCA12CA1CA2 | |
| SCHEMBL15041407 | 0.80 | RECQL (0.45) | POLBRECQLCA12CA1CA2 | |
| SCHEMBL28827551 | 0.78 | RECQL (0.44) | POLBRECQLCA12CA1CA2 | |
| SCHEMBL21034083 | 0.78 | RECQL (0.44) | POLBRECQLCA12CA1CA2 | |
| SCHEMBL27203361 | 0.78 | RECQL (0.44) | POLBRECQLCA12CA1CA2 | |
| SCHEMBL2053373 | 0.75 | KDM4E (0.45) | POLBRECQLCA12CA1CA2 | |
| SCHEMBL288348 | 0.75 | CA2 (0.39) | RECQLCA12CA1CA2CA9 | |
| SCHEMBL23701634 | 0.74 | KMT2A (0.41) | POLBRECQLCA12CA1CA2 | |
| Sulfuric Acid SCHEMBL22462539 | 0.74 | RECQL (0.41) | POLBRECQLCA12CA1CA2 | |
| SCHEMBL28801470 | 0.74 | CA12 (0.31) | POLBCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108633-A | The Imidazopyridazine derivative connected as the heterocyclic radical of PI3K beta inhibitors | 詹森药业有限公司 | 2017-08-29 | — | — | CN | disclosed |