Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | ADH1B | P00325 | 1/20 | 0.43 |
| ▸ | ADH1C | P00326 | 1/20 | 0.43 |
| ▸ | ADH1A | P07327 | 1/20 | 0.43 |
| ▸ | ADH7 | P40394 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21034368 | 0.87 | RAB9A (0.47) | IDO1MEN1KMT2AALDH1A1CA2 | |
| SCHEMBL11360130 | 0.79 | IDO1 (0.52) | IDO1MEN1KMT2ATHRBTDP1 | |
| SCHEMBL21034350 | 0.76 | L3MBTL1 (0.54) | IDO1MAPTCYP3A4KDM4EALDH1A1 | |
| SCHEMBL5355705 | 0.75 | IDO1 (0.48) | IDO1MEN1KMT2ATHRBTDP1 | |
| SCHEMBL109301 | 0.75 | CYP3A4 (0.52) | IDO1MEN1KMT2ATHRBTDP1 | |
| SCHEMBL8075682 | 0.75 | IDO1 (0.54) | IDO1MEN1KMT2ATHRBTDP1 | |
| SCHEMBL29875311 | 0.75 | IDO1 (0.48) | IDO1MEN1KMT2ATHRBTDP1 | |
| SCHEMBL149061 | 0.75 | PTPN1 (0.49) | IDO1MEN1KMT2ATHRBTDP1 | |
| SCHEMBL5790558 | 0.73 | IDO1 (0.46) | IDO1MEN1KMT2ATHRBTDP1 | |
| Hydrochloric Acid SCHEMBL10435079 | 0.73 | MAPT (0.56) | IDO1MEN1KMT2ATHRBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3715342-A1 | FLUOROSULFONYL-CONTAINING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) | 2020-09-30 | — | — | EP | disclosed |
| WO-2019101132-A1 | FLUOROSULFONYL-CONTAINING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院上海有机化学研究所 | 2019-05-31 | — | — | WO | disclosed |