Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH3A1 | P30838 | 7/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 8/20 | 0.48 |
| ▸ | CXCL8 | P10145 | 3/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7837246 | 0.82 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH3A1NOD1CXCL8NOD2 | |
| SCHEMBL28063595 | 0.82 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH3A1NOD1CXCL8NOD2 | |
| SCHEMBL22462449 | 0.82 | SMN1; SMN2 (0.66) | SMN1; SMN2ALDH3A1NOD1CXCL8NOD2 | |
| SCHEMBL3490377 | 0.78 | SMN1; SMN2 (0.74) | SMN1; SMN2ALDH3A1NOD1CXCL8NOD2 | |
| SCHEMBL24696307 | 0.76 | KDM4E (0.49) | SMN1; SMN2ALDH3A1NOD1CXCL8NOD2 | |
| SCHEMBL7837525 | 0.70 | GAA (0.61) | SMN1; SMN2ALDH3A1NOD1CXCL8NOD2 | |
| SCHEMBL24695992 | 0.69 | NOD1 (0.55) | SMN1; SMN2ALDH3A1NOD1LMNAKDM4E | |
| SCHEMBL66294 | 0.69 | SMN1; SMN2 (0.63) | SMN1; SMN2NOD1CXCL8NOD2LMNA | |
| SCHEMBL1053419 | 0.69 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNAKDM4EALDH1A1TSHR | |
| SCHEMBL3634978 | 0.68 | SMN1; SMN2 (0.66) | SMN1; SMN2ALDH3A1NOD1CXCL8NOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3715342-B1 | FLUOROSULFONYL-CONTAINING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | ZHONGHONGXIN INVEST HOLDINGS SHENZHEN CO LTD (CN) | 2024-08-07 | — | — | EP | disclosed |
| US-11091442-B2 | Fluorosulfonyl-containing compound, intermediate thereof, preparation method therefor and use thereof | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2021-08-17 | — | — | US | disclosed |
| US-11091442-B2 | Fluorosulfonyl-containing compound, intermediate thereof, preparation method therefor and use thereof | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2021-08-17 | — | — | US | disclosed |
| US-11046653-B2 | — | — | 2021-06-29 | — | — | US | disclosed |
| US-11046653-B2 | — | — | 2021-06-29 | — | — | US | disclosed |
| US-20200369619-A1 | FLUOROSULFONYL-CONTAINING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2020-11-26 | — | — | US | disclosed |
| US-20200369619-A1 | FLUOROSULFONYL-CONTAINING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2020-11-26 | — | — | US | disclosed |
| EP-3715342-A1 | FLUOROSULFONYL-CONTAINING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) | 2020-09-30 | — | — | EP | disclosed |
| CN-107857730-B | A kind of fluorosulfonyl group-containing compound, wherein mesosome, preparation method and application | 中国科学院上海有机化学研究所 | 2019-10-15 | — | — | CN | disclosed |
| WO-2019101132-A1 | FLUOROSULFONYL-CONTAINING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院上海有机化学研究所 | 2019-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11046653-B2 | — | CYP4F11, NOTUM, CYP2F1 | SMN1; SMN2 2893/4885ALDH3A1 342/4885NOD1 1166/4885 |
| US-20200369619-A1 | FLUOROSULFONYL-CONTAINING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | WEE1, NOTUM, WEE2 | SMN1; SMN2 3296/4885ALDH3A1 400/4885NOD1 329/4885 |
| US-11091442-B2 | Fluorosulfonyl-containing compound, intermediate thereof, preparation method therefor and use thereof | WEE1, NOTUM, WEE2 | SMN1; SMN2 3296/4885ALDH3A1 400/4885NOD1 329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.