Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MET | P08581 | 1/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.47 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3470253 | 0.71 | ALOX5 (0.65) | NOD1ALDH3A1ALDH1A1MEN1KMT2A | |
| SCHEMBL7837246 | 0.70 | SMN1; SMN2 (0.56) | GAANOD1ALDH3A1ALDH1A1SMN1; SMN2 | |
| SCHEMBL21034360 | 0.70 | SMN1; SMN2 (0.52) | GAANOD1ALDH3A1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3470885 | 0.69 | ALDH3A1 (0.56) | GAANOD1ALDH3A1ALDH1A1MEN1 | |
| SCHEMBL20996049 | 0.68 | MET (0.56) | GAAMETALDH1A1MEN1KMT2A | |
| SCHEMBL2360974 | 0.67 | ALDH1A1 (0.84) | ALDH1A1MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL6534916 | 0.67 | KMT2A (0.61) | GAAMETALDH1A1MEN1KMT2A | |
| SCHEMBL3490377 | 0.67 | SMN1; SMN2 (0.74) | GAANOD1ALDH3A1ALDH1A1KMT2A | |
| SCHEMBL2361629 | 0.67 | GAA (0.52) | GAAMETALDH1A1MEN1KMT2A | |
| SCHEMBL17278 | 0.66 | KMT2A (0.70) | ALDH1A1MEN1KMT2APOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977740-A4 | METHODS FOR SYNTHESIZING 2-SUBSTITUTED IMIDAZOLES | SEPRACOR INC (US) | 2001-01-17 | — | — | EP | disclosed |
| EP-0977740-A1 | METHODS FOR SYNTHESIZING 2-SUBSTITUTED IMIDAZOLES | SEPRACOR, INC. (US) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998046571-A1 | METHODS FOR SYNTHESIZING 2-SUBSTITUTED IMIDAZOLES | SEPRACOR INC. (US) | 1998-10-22 | — | — | WO | disclosed |