SCHEMBL66294

SCHEMBL66294

Clc1nc2ccccc2n1Cl

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.63
LMNA P02545 5/20 0.47
TDP1 Q9NUW8 1/20 0.42
NOS2 P35228 1/20 0.42
RAB9A P51151 2/20 0.42
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
NPC1 O15118 1/20 0.42
KMT2A Q03164 1/20 0.42
TNF P01375 3/20 0.40
NOD2 Q9HC29 2/20 0.40
NOD1 Q9Y239 2/20 0.40
CXCL8 P10145 1/20 0.40
SOS1 Q07889 1/20 0.40
GALR3 O60755 1/20 0.40
NR2F2 P24468 1/20 0.40
ATM Q13315 1/20 0.39
TYMS P04818 1/20 0.39
MAPK1 P28482 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1053419 0.77 SMN1; SMN2 (1.00) SMN1; SMN2LMNARAB9AKDM4EMEN1
SCHEMBL7394357 0.77 SMN1; SMN2 (0.52) SMN1; SMN2LMNARAB9AKDM4EMEN1
SCHEMBL2885907 0.76 HTT (0.55) SMN1; SMN2LMNARAB9AKDM4ENPC1
SCHEMBL8956416 0.76 SMN1; SMN2 (0.61) SMN1; SMN2LMNATDP1NOS2RAB9A
SCHEMBL4027582 0.76 SMN1; SMN2 (0.61) SMN1; SMN2LMNATDP1NOS2RAB9A
SCHEMBL9739302 0.74 LMNA (0.42) SMN1; SMN2LMNARAB9AKDM4EMEN1
SCHEMBL6733842 0.74 SMN1; SMN2 (0.53) SMN1; SMN2LMNARAB9AKDM4EMEN1
SCHEMBL6589381 0.72 SMN1; SMN2 (0.56) SMN1; SMN2LMNARAB9AKDM4EMEN1
SCHEMBL3373218 0.72 SMN1; SMN2 (0.42) SMN1; SMN2LMNANOS2KDM4EMEN1
SCHEMBL31759194 0.72 SMN1; SMN2 (0.74) SMN1; SMN2LMNARAB9AKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 360 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118126467-A Heat-resistant modified polyvinyl chloride power tube and preparation method thereof 杭州鼎新建科实业有限公司 2024-06-04 CN claimed
CN-111335033-A Neckerchief fabric for infant care and preparation method thereof 张海军 2020-06-26 CN claimed
US-8188254-B2 C-class oligonucleotide analogs with enhanced immunostimulatory potency COLEY PHARMACEUTICAL GMBH (DE) 2012-05-29 US claimed
EP-1978997-A1 TRANSDERMAL DELIVERY OF PHARMACEUTICAL AGENTS Apollo Life Sciences Limited (AU) 2008-10-15 EP claimed
EP-1861387-A1 NOVEL BENZOIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2007-12-05 EP claimed
WO-2007070983-A1 TRANSDERMAL DELIVERY OF PHARMACEUTICAL AGENTS APOLLO LIFE SCIENCES LIMITED (AU) 2007-06-28 WO claimed
EP-1730281-A2 IMMUNOSTIMULATORY NUCLEIC ACIDS FOR INDUCING IL-10 RESPONSES Coley Pharmaceutical Group, Inc. (US) 2006-12-13 EP claimed
EP-1728863-A2 C-class oligonucleotide analogs with enhanced immunostimulatory potency Coley Pharmaceutical GmbH (DE) 2006-12-06 EP claimed
WO-2006080821-A1 NOVEL BENZOIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2006-08-03 WO claimed
EP-1678303-A2 C-CLASS OLIGONUCLEOTIDE ANALOGS WITH ENHANCED IMMUNOSTIMULATORY POTENCY Coley Pharmaceutical GmbH (DE) 2006-07-12 EP claimed
WO-2005111057-A2 IMMUNOSTIMULATORY NUCLEIC ACIDS FOR INDUCING IL-10 RESPONSES COLEY PHARMACEUTICAL GROUP, INC. (US) 2005-11-24 WO claimed
US-20050239734-A1 C-class oligonucleotide analogs with enhanced immunostimulatory potency COLEY PHARMACEUTICAL GMBH (DE) 2005-10-27 US claimed
EP-1578954-A2 5' CPG NUCLEIC ACIDS AND METHODS OF USE Coley Pharmaceutical Group, Inc. (US) 2005-09-28 EP claimed
WO-2005042018-A2 C-CLASS OLIGONUCLEOTIDE ANALOGS WITH ENHANCED IMMUNOSTIMULATORY POTENCY COLEY PHARMACEUTICAL GMBH (DE) 2005-05-12 WO claimed
US-20040171571-A1 5' CpG nucleic acids and methods of use COLEY PHARMACEUTICAL GROUP, INC. (US) 2004-09-02 US claimed
WO-2004053104-A2 5’ CPG NUCLEIC ACIDS AND METHODS OF USE COLEY PHARMACEUTICAL GROUP, INC. (US) 2004-06-24 WO claimed
US-12637646-B2 DNA origami cell sensing platform OHIO STATE INNOVATION FOUNDATION (US) 2026-05-26 US disclosed
US-20260139247-A1 ENGINEERED ENVELOPED VECTORS AND METHODS OF USE THEREOF GIGAMUNE INC (US) 2026-05-21 US disclosed
WO-2004005476-A2 NUCLEIC ACID COMPOSITIONS FOR STIMULATING IMMUNE RESPONSES COLEY PHARMACEUTICAL GROUP, INC. (US) 2004-01-15 WO disclosed
US-4594420-A Substituted with bromine or chlorine HOECHST AKTIENGESELLSCHAFT (DE) 1986-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260139247-A1 ENGINEERED ENVELOPED VECTORS AND METHODS OF USE THEREOF TMIGD3, TMPRSS11D, TMED2 SMN1; SMN2 213/4885LMNA 1104/4885TDP1 1295/4885
US-12637646-B2 DNA origami cell sensing platform DNMT3A, EPCAM, CASR SMN1; SMN2 1592/4885LMNA 197/4885TDP1 203/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.