Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL608453 | 0.76 | TSHR (0.54) | TSHRALDH1A1MEN1KMT2ASLC6A2 | |
| SCHEMBL21034098 | 0.74 | KMT2A (0.44) | TSHRALDH1A1MEN1KMT2ASLC6A2 | |
| Hydrochloric Acid SCHEMBL27658035 | 0.74 | TSHR (0.52) | TSHRALDH1A1MEN1KMT2ASLC6A2 | |
| SCHEMBL13357040 | 0.73 | SLC6A2 (0.50) | TSHRALDH1A1MEN1KMT2ASLC6A2 | |
| SCHEMBL19174197 | 0.72 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ASLC6A2 | |
| SCHEMBL3635237 | 0.72 | TSHR (0.54) | TSHRALDH1A1MEN1KMT2ASLC6A2 | |
| Hydrochloric Acid SCHEMBL27675308 | 0.71 | TSHR (0.48) | TSHRALDH1A1MEN1KMT2ASLC6A2 | |
| SCHEMBL530326 | 0.70 | ADRA2B (0.67) | TSHRALDH1A1MEN1KMT2ASLC6A2 | |
| SCHEMBL2662419 | 0.69 | KMT2A (0.50) | TSHRALDH1A1MEN1KMT2ASLC6A2 | |
| SCHEMBL21034084 | 0.69 | TSHR (0.48) | TSHRALDH1A1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3715342-A1 | FLUOROSULFONYL-CONTAINING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) | 2020-09-30 | — | — | EP | disclosed |
| WO-2019101132-A1 | FLUOROSULFONYL-CONTAINING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院上海有机化学研究所 | 2019-05-31 | — | — | WO | disclosed |