Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 3/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LATS1 | O95835 | 1/20 | 0.37 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10087249 | 0.78 | LMNA (0.63) | LOXL2KDM4ECASRTAAR1LMNA | |
| SCHEMBL10087170 | 0.73 | CASR (0.44) | LOXL2KDM4ECASRTAAR1LMNA | |
| SCHEMBL72988 | 0.72 | ESR1 (0.58) | LOXL2KDM4ETAAR1LMNAHPGD | |
| SCHEMBL2615503 | 0.72 | ESR1 (0.58) | LOXL2KDM4ETAAR1LMNAHPGD | |
| SCHEMBL8824455 | 0.72 | KDM4E (0.42) | KDM4ECASRTAAR1LMNACYP2D6 | |
| SCHEMBL21034645 | 0.70 | HPGD (0.42) | KDM4ECASRTAAR1LMNACYP2D6 | |
| SCHEMBL8384266 | 0.70 | KDM4E (0.53) | KDM4ECASRLMNADPP4HPGD | |
| SCHEMBL9718295 | 0.70 | KDM4E (0.57) | KDM4ELMNACYP2D6DPP4HPGD | |
| SCHEMBL4661331 | 0.69 | LOXL2 (0.50) | LOXL2TAAR1LMNACYP2D6HPGD | |
| SCHEMBL25343157 | 0.69 | LOXL2 (0.48) | LOXL2TAAR1LMNAHPGDIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3715342-A1 | FLUOROSULFONYL-CONTAINING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) | 2020-09-30 | — | — | EP | disclosed |
| WO-2019101132-A1 | FLUOROSULFONYL-CONTAINING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院上海有机化学研究所 | 2019-05-31 | — | — | WO | disclosed |