Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.39 |
| ▸ | MMP9 | P14780 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 6/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | CCR3 | P51677 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035658 | 1.00 | GHSR (0.39) | GHSRMMP9CA12CA2MMP2 | |
| SCHEMBL21035524 | 0.90 | KAT6A (0.38) | GHSRMMP9MMP2AKR1C3AKR1C1 | |
| SCHEMBL21034975 | 0.88 | MMP9 (0.43) | GHSRMMP9CA12CA2MMP2 | |
| SCHEMBL21035657 | 0.88 | MMP9 (0.43) | GHSRMMP9CA12CA2MMP2 | |
| SCHEMBL21035656 | 0.86 | MCL1 (0.37) | MMP9CA12CA2MMP2 | |
| Trifluoroacetic Acid SCHEMBL21002047 | 0.83 | GHSR (0.40) | GHSRMMP9CA12CA2MMP2 | |
| SCHEMBL21035353 | 0.78 | GHSR (0.43) | GHSRMMP9CA12CA2MMP2 | |
| SCHEMBL21034980 | 0.78 | GHSR (0.43) | GHSRMMP9CA12CA2MMP2 | |
| SCHEMBL21034984 | 0.77 | CA12 (0.48) | GHSRMMP9CA12CA2MMP2 | |
| SCHEMBL21035346 | 0.77 | CA12 (0.48) | GHSRMMP9CA12CA2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |