Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 4/20 | 0.38 |
| ▸ | MMP3 | P08254 | 4/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | USP5 | P45974 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 3/20 | 0.35 |
| ▸ | GHSR | Q92847 | 3/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035658 | 0.90 | GHSR (0.39) | MMP9AKR1C3AKR1C1HCRTR1HCRTR2 | |
| SCHEMBL21034976 | 0.90 | GHSR (0.39) | MMP9AKR1C3AKR1C1HCRTR1HCRTR2 | |
| SCHEMBL21035523 | 0.86 | AKR1C3 (0.43) | KAT6AMMP1MMP3MMP9ADAM17 | |
| SCHEMBL21035522 | 0.82 | MMP1 (0.43) | KAT6AMMP1MMP3MMP9ADAM17 | |
| SCHEMBL21035353 | 0.82 | GHSR (0.43) | MMP1MMP3MMP9ADAM17AKR1C3 | |
| SCHEMBL21034980 | 0.82 | GHSR (0.43) | MMP1MMP3MMP9ADAM17AKR1C3 | |
| SCHEMBL21035346 | 0.81 | CA12 (0.48) | MMP1MMP3MMP9ADAM17AKR1C3 | |
| SCHEMBL21034984 | 0.81 | CA12 (0.48) | MMP1MMP3MMP9ADAM17AKR1C3 | |
| SCHEMBL21035399 | 0.78 | HTR1A (0.44) | MMP1MMP3MMP9ADAM17AKR1C3 | |
| SCHEMBL21035314 | 0.78 | HTR1A (0.44) | MMP1MMP3MMP9ADAM17AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |