Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.42 |
| ▸ | MMP9 | P14780 | 4/20 | 0.42 |
| ▸ | MMP13 | P45452 | 3/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | MMP7 | P09237 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 3/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.38 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035474 | 1.00 | MMP1 (0.42) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL21035608 | 1.00 | MMP1 (0.42) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL21035503 | 0.90 | EPHX2 (0.39) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL21035600 | 0.88 | MEN1 (0.41) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL21035442 | 0.88 | MEN1 (0.41) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL21035340 | 0.88 | MEN1 (0.41) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL21035480 | 0.86 | GHSR (0.46) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL21035105 | 0.86 | GHSR (0.46) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL21035611 | 0.86 | GHSR (0.46) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL21035072 | 0.85 | CCR4 (0.42) | MMP1MMP9MMP13MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |