Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MMP13 | P45452 | 2/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035611 | 1.00 | GHSR (0.46) | GHSRMEN1KMT2AMMP1MMP9 | |
| SCHEMBL21035105 | 1.00 | GHSR (0.46) | GHSRMEN1KMT2AMMP1MMP9 | |
| SCHEMBL21035506 | 0.89 | GHSR (0.44) | GHSRMMP1MMP9MMP13MMP3 | |
| SCHEMBL21035104 | 0.86 | MMP1 (0.42) | MEN1KMT2AMMP1MMP9MMP13 | |
| SCHEMBL21035474 | 0.86 | MMP1 (0.42) | MEN1KMT2AMMP1MMP9MMP13 | |
| SCHEMBL21035608 | 0.86 | MMP1 (0.42) | MEN1KMT2AMMP1MMP9MMP13 | |
| SCHEMBL21035443 | 0.85 | GHSR (0.47) | GHSRMEN1KMT2AMMP1MMP9 | |
| SCHEMBL21035342 | 0.85 | GHSR (0.47) | GHSRMEN1KMT2AMMP1MMP9 | |
| SCHEMBL21035601 | 0.85 | GHSR (0.47) | GHSRMEN1KMT2AMMP1MMP9 | |
| SCHEMBL21035071 | 0.82 | GHSR (0.46) | GHSRMEN1KMT2AMMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |