Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 18/20 | 0.55 |
| ▸ | MMP1 | P03956 | 16/20 | 0.55 |
| ▸ | MMP13 | P45452 | 2/20 | 0.51 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | MMP7 | P09237 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035334 | 1.00 | ADAM17 (0.55) | ADAM17MMP1MMP13MMP3MMP7 | |
| SCHEMBL21035084 | 1.00 | ADAM17 (0.55) | ADAM17MMP1MMP13MMP3MMP7 | |
| SCHEMBL21035416 | 1.00 | ADAM17 (0.55) | ADAM17MMP1MMP13MMP3MMP7 | |
| SCHEMBL21035122 | 1.00 | ADAM17 (0.55) | ADAM17MMP1MMP13MMP3MMP7 | |
| SCHEMBL21034929 | 0.91 | MMP1 (0.46) | ADAM17MMP1MMP13MMP3MMP7 | |
| SCHEMBL21036191 | 0.91 | MMP1 (0.46) | ADAM17MMP1MMP13MMP3MMP7 | |
| SCHEMBL21035661 | 0.87 | MMP1 (0.46) | ADAM17MMP1MMP13MMP3MMP7 | |
| SCHEMBL21035390 | 0.84 | ADAM17 (0.47) | ADAM17MMP1MMP13MMP3MMP7 | |
| SCHEMBL21035335 | 0.84 | MMP1 (0.47) | ADAM17MMP1MMP13MMP3MMP7 | |
| SCHEMBL21035339 | 0.84 | MMP1 (0.47) | ADAM17MMP1MMP13MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |