Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 13/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 9/20 | 0.46 |
| ▸ | MMP3 | P08254 | 8/20 | 0.46 |
| ▸ | MMP7 | P09237 | 7/20 | 0.46 |
| ▸ | MMP13 | P45452 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 3/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21034929 | 1.00 | MMP1 (0.46) | MMP1ADAM17MMP3MMP7MMP13 | |
| SCHEMBL21035122 | 0.91 | ADAM17 (0.55) | MMP1ADAM17MMP3MMP7MMP13 | |
| SCHEMBL21035334 | 0.91 | ADAM17 (0.55) | MMP1ADAM17MMP3MMP7MMP13 | |
| SCHEMBL21035416 | 0.91 | ADAM17 (0.55) | MMP1ADAM17MMP3MMP7MMP13 | |
| SCHEMBL21035124 | 0.91 | ADAM17 (0.55) | MMP1ADAM17MMP3MMP7MMP13 | |
| SCHEMBL21035084 | 0.91 | ADAM17 (0.55) | MMP1ADAM17MMP3MMP7MMP13 | |
| SCHEMBL21034928 | 0.84 | MMP1 (0.42) | MMP1ADAM17MMP3MMP7MMP13 | |
| SCHEMBL21036192 | 0.84 | MMP1 (0.42) | MMP1ADAM17MMP3MMP7MMP13 | |
| SCHEMBL8144145 | 0.82 | MMP1 (0.62) | MMP1ADAM17MMP3MMP7MMP13 | |
| SCHEMBL8498279 | 0.82 | MMP1 (0.62) | MMP1ADAM17MMP3MMP7MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |