SCHEMBL21035286

SCHEMBL21035286

c1ccc(-c2ccc3c(c2)c2ccccc2c2c4ccc(-c5ccc(-c6cccc7oc8ccccc8c67)cc5)cc4c4ccccc4c32)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 5/20 0.43
PLA2G4A P47712 5/20 0.43
PLA2G10 O15496 1/20 0.42
ALOX5 P09917 1/20 0.38
CASP3 P42574 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
HCRTR1 O43613 1/20 0.36
HPGD P15428 2/20 0.36
GABRP O00591 1/20 0.36
GABRD O14764 1/20 0.36
NPC1 O15118 1/20 0.36
CA12 O43570 1/20 0.36
TNKS O95271 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
TP53 P04637 1/20 0.36
ABCB1 P08183 1/20 0.36
CYP3A4 P08684 1/20 0.36
PARP1 P09874 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21034889 0.97 PLA2G2A (0.43) PLA2G2APLA2G4APLA2G10ALOX5CASP3
SCHEMBL21035282 0.97 PLA2G2A (0.40) PLA2G2APLA2G4APLA2G10ALOX5CASP3
SCHEMBL25081967 0.94 PLA2G2A (0.44) PLA2G2APLA2G4APLA2G10ALOX5CASP3
SCHEMBL25140453 0.94 PLA2G2A (0.47) PLA2G2APLA2G4APLA2G10ALOX5CASP3
SCHEMBL16904371 0.94 PLA2G2A (0.42) PLA2G2APLA2G4APLA2G10ALOX5CASP3
SCHEMBL25140451 0.93 PLA2G2A (0.46) PLA2G2APLA2G4APLA2G10ALOX5CASP3
SCHEMBL21035284 0.92 PLA2G2A (0.42) PLA2G2APLA2G4APLA2G10ALOX5CASP3
SCHEMBL25140572 0.91 PLA2G2A (0.47) PLA2G2APLA2G4APLA2G10ALOX5CASP3
SCHEMBL21034884 0.91 ALOX5 (0.44) PLA2G2APLA2G4APLA2G10ALOX5CASP3
SCHEMBL21034882 0.91 ALOX5 (0.44) PLA2G2APLA2G4APLA2G10ALOX5CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190165279-A1 ORGANIC ELECTROLUMINESCENT ELEMENT JNC CORPORATION (JP) 2019-05-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190165279-A1 ORGANIC ELECTROLUMINESCENT ELEMENT TCF4, LGR4, OR51E2 PLA2G2A 2960/4885PLA2G4A 2931/4885PLA2G10 2966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.