Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 3/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.41 |
| ▸ | MMP1 | P03956 | 4/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.41 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 3/20 | 0.39 |
| ▸ | MMP7 | P09237 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21036250 | 1.00 | HCRTR1 (0.41) | HCRTR1HCRTR2MMP1ADAM17KCNQ1 | |
| SCHEMBL21035451 | 0.98 | HCRTR1 (0.41) | HCRTR1HCRTR2MMP1ADAM17KCNQ1 | |
| SCHEMBL21035367 | 0.92 | MMP1 (0.41) | HCRTR1HCRTR2MMP1ADAM17KCNQ1 | |
| SCHEMBL21035323 | 0.92 | HCRTR1 (0.43) | HCRTR1HCRTR2MMP1ADAM17KCNQ1 | |
| SCHEMBL21035449 | 0.90 | MMP1 (0.41) | HCRTR1HCRTR2MMP1ADAM17KCNQ1 | |
| SCHEMBL21035063 | 0.89 | CACNA1A (0.44) | HCRTR1HCRTR2MMP1ADAM17KCNQ1 | |
| SCHEMBL21002021 | 0.87 | PSEN1 (0.40) | MMP1ADAM17MMP3MMP7MMP13 | |
| SCHEMBL21001901 | 0.87 | PSEN1 (0.40) | MMP1ADAM17MMP3MMP7MMP13 | |
| SCHEMBL21002019 | 0.87 | PSEN1 (0.40) | MMP1ADAM17MMP3MMP7MMP13 | |
| SCHEMBL21002020 | 0.87 | PSEN1 (0.40) | MMP1ADAM17MMP3MMP7MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |