Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | BRD2 | P25440 | 1/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035449 | 0.98 | MMP1 (0.41) | MMP1ADAM17PSEN1PSEN2APH1B | |
| SCHEMBL21035366 | 0.92 | HCRTR1 (0.41) | MMP1ADAM17PSEN1PSEN2APH1B | |
| SCHEMBL21036250 | 0.92 | HCRTR1 (0.41) | MMP1ADAM17PSEN1PSEN2APH1B | |
| SCHEMBL21035326 | 0.91 | MMP1 (0.42) | MMP1ADAM17BRD4MAPTITGB1 | |
| SCHEMBL21035451 | 0.90 | HCRTR1 (0.41) | MMP1ADAM17PSEN1PSEN2APH1B | |
| SCHEMBL21035064 | 0.89 | LMNA (0.45) | MMP1ADAM17BRD4MAPTITGB1 | |
| SCHEMBL21002021 | 0.89 | PSEN1 (0.40) | MMP1ADAM17PSEN1PSEN2APH1B | |
| SCHEMBL21035364 | 0.89 | PSEN1 (0.40) | MMP1ADAM17PSEN1PSEN2APH1B | |
| SCHEMBL21002020 | 0.89 | PSEN1 (0.40) | MMP1ADAM17PSEN1PSEN2APH1B | |
| SCHEMBL21002063 | 0.89 | PSEN1 (0.40) | MMP1ADAM17PSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |