Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 4/20 | 0.37 |
| ▸ | MMP3 | P08254 | 4/20 | 0.37 |
| ▸ | MMP9 | P14780 | 3/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 3/20 | 0.35 |
| ▸ | CCR4 | P51679 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035354 | 0.97 | MCL1 (0.39) | L3MBTL1KMT2AMMP3MMP9MMP2 | |
| SCHEMBL21034978 | 0.97 | MCL1 (0.39) | L3MBTL1KMT2AMMP3MMP9MMP2 | |
| SCHEMBL21035316 | 0.93 | MMP9 (0.36) | L3MBTL1KMT2AMMP1MMP3MMP9 | |
| SCHEMBL21035404 | 0.93 | MMP9 (0.36) | L3MBTL1KMT2AMMP1MMP3MMP9 | |
| SCHEMBL21035406 | 0.92 | KMT2A (0.36) | L3MBTL1KMT2AMMP1MMP3MMP9 | |
| SCHEMBL21034983 | 0.91 | MCL1 (0.38) | L3MBTL1KMT2AMMP9MMP2MCL1 | |
| SCHEMBL21035667 | 0.87 | ITGB1 (0.39) | L3MBTL1KMT2AHCRTR1HCRTR2 | |
| SCHEMBL21035131 | 0.86 | ITGB1 (0.38) | L3MBTL1KMT2AMCL1HCRTR1HCRTR2 | |
| SCHEMBL21035008 | 0.86 | ITGB1 (0.38) | L3MBTL1KMT2AMCL1HCRTR1HCRTR2 | |
| SCHEMBL21035619 | 0.85 | MMP9 (0.37) | L3MBTL1KMT2AMMP1MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |