Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 12/20 | 0.36 |
| ▸ | MMP9 | P14780 | 3/20 | 0.35 |
| ▸ | BCL2 | P10415 | 4/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 3/20 | 0.34 |
| ▸ | MMP3 | P08254 | 3/20 | 0.34 |
| ▸ | MMP7 | P09237 | 3/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035520 | 0.92 | L3MBTL1 (0.39) | KMT2AL3MBTL1MCL1MMP9MMP2 | |
| SCHEMBL21034983 | 0.90 | MCL1 (0.38) | KMT2AL3MBTL1MCL1MMP9BCL2 | |
| SCHEMBL21034978 | 0.89 | MCL1 (0.39) | KMT2AL3MBTL1MCL1MMP9BCL2 | |
| SCHEMBL21035354 | 0.89 | MCL1 (0.39) | KMT2AL3MBTL1MCL1MMP9BCL2 | |
| SCHEMBL21036274 | 0.89 | MMP9 (0.35) | KMT2AL3MBTL1MCL1MMP9BCL2 | |
| SCHEMBL21035316 | 0.89 | MMP9 (0.36) | KMT2AL3MBTL1MCL1MMP9BCL2 | |
| SCHEMBL21035404 | 0.89 | MMP9 (0.36) | KMT2AL3MBTL1MCL1MMP9BCL2 | |
| SCHEMBL21036275 | 0.87 | MMP9 (0.38) | MMP9MMP2MMP1MMP3MMP7 | |
| SCHEMBL21035407 | 0.87 | MMP9 (0.38) | MMP9MMP2MMP1MMP3MMP7 | |
| Trifluoroacetic Acid SCHEMBL21002135 | 0.85 | MMP9 (0.35) | MCL1MMP9MMP2MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |