Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 8/20 | 0.37 |
| ▸ | MMP2 | P08253 | 7/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MMP3 | P08254 | 3/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.34 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.34 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035404 | 0.92 | MMP9 (0.36) | MMP9MMP2KMT2AMMP3MMP1 | |
| SCHEMBL21035316 | 0.92 | MMP9 (0.36) | MMP9MMP2KMT2AMMP3MMP1 | |
| SCHEMBL21035667 | 0.88 | ITGB1 (0.39) | KMT2AGPR119CACNB4CACNA1ACACNA1G | |
| SCHEMBL21035615 | 0.88 | GHSR (0.38) | MMP9MMP2MMP3MMP1MMP7 | |
| SCHEMBL21035612 | 0.88 | GHSR (0.38) | MMP9MMP2MMP3MMP1MMP7 | |
| SCHEMBL21035614 | 0.88 | GHSR (0.38) | MMP9MMP2MMP3MMP1MMP7 | |
| SCHEMBL21035008 | 0.87 | ITGB1 (0.38) | KMT2AGPR119CACNB4CACNA1ACACNA1G | |
| SCHEMBL21035131 | 0.87 | ITGB1 (0.38) | KMT2AGPR119CACNB4CACNA1ACACNA1G | |
| SCHEMBL21035520 | 0.85 | L3MBTL1 (0.39) | MMP9MMP2KMT2AMMP3MMP1 | |
| SCHEMBL21036232 | 0.85 | CCR4 (0.38) | MMP9KMT2AMMP3MMP1MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |