Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.60 |
| ▸ | ANPEP | P15144 | 3/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 6/20 | 0.41 |
| ▸ | MMP1 | P03956 | 4/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 3/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035533 | 0.85 | CASP3 (0.56) | CASP3MMP3MMP1HCRTR1HCRTR2 | |
| SCHEMBL21034979 | 0.82 | MMP1 (0.45) | MMP2CASP3MMP3MMP1HCRTR1 | |
| SCHEMBL21035318 | 0.82 | MMP1 (0.43) | MMP2CASP3MMP3MMP1HCRTR1 | |
| SCHEMBL21035402 | 0.82 | MMP1 (0.43) | MMP2CASP3MMP3MMP1HCRTR1 | |
| SCHEMBL21034981 | 0.82 | MMP1 (0.45) | MMP2CASP3MMP3MMP1HCRTR1 | |
| SCHEMBL21035010 | 0.81 | MMP1 (0.47) | CASP3MMP3MMP1HCRTR1HCRTR2 | |
| SCHEMBL21035002 | 0.81 | MMP1 (0.47) | CASP3MMP3MMP1HCRTR1HCRTR2 | |
| SCHEMBL21035522 | 0.80 | MMP1 (0.43) | MMP2ANPEPCASP3MMP3MMP1 | |
| SCHEMBL6640295 | 0.79 | MMP2 (0.79) | MMP2ANPEPMMP3MMP1MMP9 | |
| SCHEMBL8498626 | 0.79 | MMP2 (0.79) | MMP2ANPEPMMP3MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |