Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | KDM4D | Q6B0I6 | 4/20 | 0.33 |
| ▸ | KDM6A | O15550 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 3/20 | 0.32 |
| ▸ | MMP1 | P03956 | 2/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035628 | 0.86 | KMT2A (0.40) | ACACBCHRM2CHRM1MMP13MMP1 | |
| SCHEMBL21035631 | 0.77 | CHRM2 (0.42) | CHRM2CHRM1BCL2L1MCL1MMP13 | |
| SCHEMBL21035630 | 0.77 | CHRM2 (0.42) | CHRM2CHRM1BCL2L1MCL1MMP13 | |
| SCHEMBL21035632 | 0.77 | CHRM2 (0.43) | CHRM2CHRM1BCL2L1MCL1MMP1 | |
| SCHEMBL21035634 | 0.77 | CHRM2 (0.43) | CHRM2CHRM1BCL2L1MCL1MMP1 | |
| SCHEMBL21035070 | 0.75 | MMP1 (0.43) | MMP13MMP1ADAM17MMP3ALOX5 | |
| SCHEMBL21035598 | 0.75 | MMP1 (0.43) | MMP13MMP1ADAM17MMP3ALOX5 | |
| SCHEMBL21035340 | 0.75 | MEN1 (0.41) | MMP13MMP1ADAM17MMP3ALOX5 | |
| SCHEMBL21035600 | 0.75 | MEN1 (0.41) | MMP13MMP1ADAM17MMP3ALOX5 | |
| SCHEMBL21035442 | 0.75 | MEN1 (0.41) | MMP13MMP1ADAM17MMP3ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |