Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.42 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 3/20 | 0.40 |
| ▸ | MMP1 | P03956 | 3/20 | 0.40 |
| ▸ | MMP7 | P09237 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035630 | 1.00 | CHRM2 (0.42) | CHRM2KCNQ1CHRM1KMT2AALDH1A1 | |
| SCHEMBL21035632 | 0.92 | CHRM2 (0.43) | CHRM2KCNQ1CHRM1KMT2AALDH1A1 | |
| SCHEMBL21035634 | 0.92 | CHRM2 (0.43) | CHRM2KCNQ1CHRM1KMT2AALDH1A1 | |
| SCHEMBL21002001 | 0.87 | GHSR (0.45) | CHRM2KCNQ1CHRM1KMT2ANPSR1 | |
| SCHEMBL21035633 | 0.87 | GHSR (0.45) | CHRM2KCNQ1CHRM1KMT2ANPSR1 | |
| SCHEMBL21001945 | 0.87 | GHSR (0.45) | CHRM2KCNQ1CHRM1KMT2ANPSR1 | |
| SCHEMBL21035573 | 0.82 | LMNA (0.48) | KMT2AALDH1A1NPSR1MMP3MMP1 | |
| SCHEMBL21035356 | 0.82 | LMNA (0.48) | KMT2AALDH1A1NPSR1MMP3MMP1 | |
| SCHEMBL21035083 | 0.81 | MMP1 (0.46) | KCNQ1KMT2ANPSR1BCL2L1MCL1 | |
| SCHEMBL21035659 | 0.81 | MMP1 (0.46) | KCNQ1KMT2ANPSR1BCL2L1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |