Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 7/20 | 0.37 |
| ▸ | MMP1 | P03956 | 6/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.37 |
| ▸ | CCR4 | P51679 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 4/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 2/20 | 0.35 |
| ▸ | MMP7 | P09237 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035598 | 0.88 | MMP1 (0.43) | KMT2AMEN1MMP13MMP1ADAM17 | |
| SCHEMBL21035070 | 0.88 | MMP1 (0.43) | KMT2AMEN1MMP13MMP1ADAM17 | |
| SCHEMBL21035340 | 0.88 | MEN1 (0.41) | KMT2AMEN1MMP13MMP1ADAM17 | |
| SCHEMBL21035600 | 0.88 | MEN1 (0.41) | KMT2AMEN1MMP13MMP1ADAM17 | |
| SCHEMBL21035442 | 0.88 | MEN1 (0.41) | KMT2AMEN1MMP13MMP1ADAM17 | |
| SCHEMBL21035633 | 0.87 | GHSR (0.45) | KMT2AMEN1MMP13MMP1MMP9 | |
| SCHEMBL21001945 | 0.87 | GHSR (0.45) | KMT2AMEN1MMP13MMP1MMP9 | |
| SCHEMBL21002001 | 0.87 | GHSR (0.45) | KMT2AMEN1MMP13MMP1MMP9 | |
| SCHEMBL21035635 | 0.86 | ACACB (0.38) | ACACBMMP13MMP1ADAM17CCR4 | |
| SCHEMBL21035321 | 0.84 | ACACB (0.39) | ACACBMMP13MMP1ADAM17MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |