Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 5/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 3/20 | 0.38 |
| ▸ | MMP13 | P45452 | 3/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.37 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.37 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.37 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21034973 | 0.96 | GPR119 (0.39) | GPR119PRKAA2CHRM1HTR2AMCHR1 | |
| SCHEMBL21035636 | 0.94 | GPR119 (0.39) | GPR119PRKAA2MMP1MMP13ADAM17 | |
| SCHEMBL21035508 | 0.94 | SCN9A (0.41) | GPR119MMP1MMP13ADAM17MMP9 | |
| SCHEMBL21036229 | 0.94 | GPR119 (0.39) | GPR119MMP1MMP13ADAM17MMP9 | |
| SCHEMBL21034944 | 0.94 | PRKAA2 (0.40) | PRKAA2MMP1MMP13ADAM17MMP9 | |
| SCHEMBL21034960 | 0.92 | GPR119 (0.40) | GPR119PRKAA2MMP1MMP13ADAM17 | |
| SCHEMBL21035090 | 0.92 | GPR119 (0.40) | GPR119PRKAA2MMP1MMP13ADAM17 | |
| SCHEMBL21035530 | 0.90 | MMP1 (0.39) | PRKAA2MMP1MMP13ADAM17MMP9 | |
| SCHEMBL21035600 | 0.88 | MEN1 (0.41) | MMP1MMP13ADAM17MMP9 | |
| SCHEMBL21035442 | 0.88 | MEN1 (0.41) | MMP1MMP13ADAM17MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |