Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | MMP1 | P03956 | 6/20 | 0.37 |
| ▸ | MMP13 | P45452 | 5/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.37 |
| ▸ | MMP9 | P14780 | 3/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 2/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035636 | 0.94 | GPR119 (0.39) | SCN9AGPR119MMP1MMP13ADAM17 | |
| SCHEMBL21035641 | 0.94 | GPR119 (0.39) | KCNQ1GPR119MMP1MMP13ADAM17 | |
| SCHEMBL21035604 | 0.94 | SCN9A (0.39) | SCN9AKCNQ1MMP1MMP13ADAM17 | |
| SCHEMBL21035570 | 0.93 | MMP1 (0.40) | SCN9AMMP1MMP13ADAM17MMP9 | |
| SCHEMBL21036229 | 0.93 | GPR119 (0.39) | KCNQ1GPR119MMP1MMP13ADAM17 | |
| SCHEMBL21034960 | 0.92 | GPR119 (0.40) | SCN9AGPR119MMP1MMP13ADAM17 | |
| SCHEMBL21034973 | 0.92 | GPR119 (0.39) | KCNQ1GPR119MMP1MMP13ADAM17 | |
| SCHEMBL21035090 | 0.91 | GPR119 (0.40) | KCNQ1GPR119MMP1MMP13ADAM17 | |
| SCHEMBL21035530 | 0.89 | MMP1 (0.39) | MMP1MMP13ADAM17MMP9MMP3 | |
| SCHEMBL21035509 | 0.88 | KCNQ1 (0.40) | KCNQ1MMP1MMP13ADAM17MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |