Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.43 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17038770 | 0.91 | TUBB4A (0.46) | ALDH1A1MAPTHTTKMT2ACNR2 | |
| SCHEMBL21036097 | 0.90 | HDAC1 (0.44) | POLBALDH1A1MAPTTP53KMT2A | |
| SCHEMBL23188087 | 0.89 | HTR6 (0.42) | POLBALDH1A1MAPTSMN1; SMN2TP53 | |
| SCHEMBL21036909 | 0.87 | HTT (0.48) | POLBALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL23188054 | 0.84 | HSD17B13 (0.39) | ALDH1A1 | |
| SCHEMBL17195555 | 0.76 | HDAC6 (0.57) | POLBALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL17039017 | 0.75 | MEN1 (0.52) | POLBALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL17038755 | 0.75 | POLB (0.52) | POLBALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL17199375 | 0.74 | POLB (0.51) | POLBALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL17038739 | 0.74 | POLB (0.51) | POLBALDH1A1MAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3107902-B1 | COMPOUNDS AND METHODS FOR INHIBITING FASCIN | CORNELL UNIV CORNELL CENTER FOR TECHNOLOGY ENTERPRISE & COMMERCIALIZATION CCTEC (US) | 2021-04-07 | — | — | EP | disclosed |
| WO-2019104067-A1 | CO-THERAPIES INCLUDING A METASTASIS INHIBITOR | CORNELL UNIVERSITY (US) | 2019-05-31 | — | — | WO | disclosed |