Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | NPM1 | P06748 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SNCA | P37840 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | ITK | Q08881 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17038770 | 0.88 | TUBB4A (0.46) | HTTMAPTNPSR1PTGS2CNR2 | |
| SCHEMBL21036097 | 0.87 | HDAC1 (0.44) | POLBMAPTNPSR1KMT2AMEN1 | |
| SCHEMBL21036099 | 0.87 | POLB (0.48) | HTTLMNAPOLBMAPTCNR2 | |
| SCHEMBL23188087 | 0.85 | HTR6 (0.42) | POLBMAPTPTGS2FAAHALDH1A1 | |
| SCHEMBL23188054 | 0.79 | HSD17B13 (0.39) | ALDH1A1CHRM1HDAC1HDAC2HDAC8 | |
| SCHEMBL17039057 | 0.78 | HSD17B13 (0.36) | POLBALDH1A1 | |
| SCHEMBL17039054 | 0.76 | HTT (0.51) | HTTLMNAPOLBMAPTNPSR1 | |
| SCHEMBL17039070 | 0.76 | HTT (0.53) | HTTLMNAPOLBMAPTNPSR1 | |
| SCHEMBL17039066 | 0.76 | HTT (0.51) | HTTLMNAPOLBMAPTNPSR1 | |
| SCHEMBL17039063 | 0.74 | HTT (0.56) | HTTLMNAPOLBMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104067-A1 | CO-THERAPIES INCLUDING A METASTASIS INHIBITOR | CORNELL UNIVERSITY (US) | 2019-05-31 | — | — | WO | disclosed |