SCHEMBL21036133

SCHEMBL21036133

C=Cc1cccc(C#N)c1-c1c(N)cccc1C#N

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
MAP2K1 Q02750 1/20 0.33
HTT P42858 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21899485 0.83 CYP3A4 (0.50) CYP1A2CYP3A4CYP2C9CYP2C19MAP2K1
SCHEMBL16958520 0.76 ALDH1A1 (0.35) MAP2K1HTTALDH1A1TSHR
SCHEMBL8150226 0.74 LMNA (0.38) HTTALDH1A1TSHR
SCHEMBL2418536 0.74 ALDH1A1 (0.34) CYP1A2CYP3A4CYP2C9CYP2C19MAP2K1
SCHEMBL30536365 0.73 TSHR (0.44) CYP1A2CYP3A4CYP2C9CYP2C19HTT
SCHEMBL183840 0.73 TSHR (0.44) CYP1A2CYP3A4CYP2C9CYP2C19HTT
SCHEMBL28232787 0.72 ESR2 (0.40) CYP1A2CYP2C9CYP2C19ALDH1A1MEN1
SCHEMBL60842 0.72 SMN1; SMN2 (0.37) HTTALDH1A1TSHRMEN1KMT2A
Benzene SCHEMBL28861778 0.71 TSHR (0.43) CYP1A2CYP3A4CYP2C9CYP2C19HTT
SCHEMBL16954087 0.71 ALDH1A1 (0.34) HTTALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3490023-A1 COMPOSITION, THIN FILM INCLUDING THE COMPOSITION, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE THIN FILM Samsung Electronics Co., Ltd. (KR) 2019-05-29 EP disclosed