Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20096182 | 0.80 | KDM2B (0.42) | L3MBTL3KDM2BHRH3 | |
| SCHEMBL20095966 | 0.80 | KDM2B (0.42) | L3MBTL3KDM2BHRH3 | |
| SCHEMBL20095968 | 0.80 | KDM2B (0.42) | L3MBTL3KDM2BHRH3 | |
| SCHEMBL23588931 | 0.78 | L3MBTL3 (0.33) | L3MBTL3KDM2B | |
| SCHEMBL15014587 | 0.77 | KDM2B (0.37) | L3MBTL3ALDH1A1KDM2BKDM4E | |
| SCHEMBL17285903 | 0.77 | ALDH1A1 (0.41) | L3MBTL3ALDH1A1KDM2BHRH3 | |
| SCHEMBL23589017 | 0.74 | HRH3 (0.33) | ALDH1A1KDM2BKDM4EHRH3 | |
| SCHEMBL24854194 | 0.74 | HRH3 (0.33) | ALDH1A1KDM2BKDM4EHRH3 | |
| SCHEMBL18673328 | 0.73 | KDM2B (0.38) | L3MBTL3KDM2B | |
| SCHEMBL12384697 | 0.73 | OPRL1 (0.38) | KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489231-A1 | PIPERAZINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2019-05-29 | — | — | EP | disclosed |