Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.44 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | HSF1 | Q00613 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15660991 | 0.78 | MAPT (0.61) | MAPTMEN1KMT2AMAPK1RAB9A | |
| SCHEMBL21160734 | 0.78 | MAPT (0.59) | MAPTMEN1KMT2AMAPK1RAB9A | |
| SCHEMBL15660986 | 0.78 | MAPT (0.61) | MAPTMEN1KMT2AMAPK1RAB9A | |
| SCHEMBL15660988 | 0.78 | MAPT (0.61) | MAPTMEN1KMT2AMAPK1RAB9A | |
| SCHEMBL14518023 | 0.71 | MAPT (0.58) | MAPTMEN1KMT2AMAPK1RAB9A | |
| SCHEMBL21037399 | 0.70 | TTR (0.43) | MAPTMEN1KMT2AMAPK1RAB9A | |
| SCHEMBL13050439 | 0.70 | MAPT (0.64) | MAPTMEN1KMT2AMAPK1RAB9A | |
| SCHEMBL11929986 | 0.69 | ELANE (0.50) | MAPTKDM4EALDH1A1LMNAUSP2 | |
| SCHEMBL23902532 | 0.69 | XDH (0.51) | MAPTMEN1KMT2AMAPK1RAB9A | |
| SCHEMBL14110401 | 0.69 | FAAH (0.47) | MAPTRAB9ANPC1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489324-A1 | FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF | East China University of Science and Technology (CN) | 2019-05-29 | — | — | EP | disclosed |